TM30339

Target: Y4
Status: Phase I/II

TM30339 works through the Y4 receptor like the natural satiety hormone, Pancreatic Polypeptide (PP), but TM30339 has improved properties over PP. Thus, TM30339 mimics a natural satiety signal from the gastrointestinal tract involved in the regulation of food intake in man. In pre-clinical studies in diet-induced obese mice, the Y4 receptor selective TM30339 was highly efficacious with respect to long term body weight reduction.